Background and aims there are limited data on the association between serum uric acid (sua) level and subclinical coronary atherosclerosis this study investigated the influence of sua level on subclinical coronary atherosclerosis, as detected by coronary computed tomography angiography (ccta), in an asymptomatic population. Uric acid and subclinical atherosclerosis. Associations of serum uric acid with markers of inflammation, metabolic syndrome, and subclinical coronary atherosclerosis coutinho tde a(1), turner st, peyser pa, bielak lf, sheedy pf 2nd, kullo ij author information: (1)department of internal medicine, mayo college of medicine, 200 first street sw, rochester, mn 55905, usa.
uric acid and subclinical atherosclerosis
Uric acid (ua) is the main end product of metabolism of purines, which in turn are derived mostly from diet, de novo biosynthesis, and breakdown of nucleic acids 1 serum ua levels, therefore, increase with higher protein intake, increased endogenous production of urate, or decreased excretion of monosodium urate by the kidneys 1 more than 50 years ago, gertler and co-workers 2 noted an. Fukui m, tanaka m, shiraishi e, harusato i, hosoda h, asano m, kadono m, hasegawa g, yoshikawa t, nakamura n. serum uric acid is associated with microalbuminuria and subclinical atherosclerosis in men with type 2 diabetes mellitus. metabolism 2008; 57:625–629.
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